Home Topics Business Analysis-Chile's COVID-19 vaccine drive is shifting to second doses due to protection...

Analysis-Chile’s COVID-19 vaccine drive is shifting to second doses due to protection and supply concerns

© Reuters. FILE PHOTO: Coronavirus disease (COVID-19) vaccination campaign in Chile


By Aislinn Laing

SANTIAGO (Reuters) – Chile is shifting its COVID-19 vaccination strategy to giving second doses while slowing down the administration of new vaccinations amid concerns about supply shortages and data showing poor protection against a dose of the Sinovac Biotech vaccine that does The backbone of formed his campaign.

The Andean nation, which had one of the world’s leading COVID-19 vaccination programs, has put more than 13 million shots in its arms and about 2 million doses still in its warehouses as of Monday, according to official figures.

Currently, clinics are distributing an average of 153,000 vaccinations per day – well below the March level – as Chile aims to reach 15 million people, about 80% of its target audience, and aims to create some level of herd immunity by the middle of the year.

This requires 2.3 million people to be vaccinated with a second dose of one of the two vaccines currently used in Chile – China’s Sinovac and Pfizer Inc (NYSE 🙂 – and vaccinate 7.3 million more people.

However, in the past few days, according to Reuters witnesses, clinics in the capital Santiago were running low on both vaccines, which turned people away or asked them to wait several hours for more to arrive.

More than 280,000 doses of the Pfizer / BioNTech shot and the first batch of 800,000 AstraZeneca (NASDAQ 🙂 Plc doses that Chile will receive from the COVAX vaccination program are expected to arrive in the coming week, the government said.

In addition, Chile is working on further supply agreements to keep its vaccination program on track.

The country is due 700,000 remaining doses of the 14.2 million it ordered for Sinovac’s CoronaVac vaccine, which helped fuel a mass vaccination campaign launched in February that Latin America was the envy of.

Chile is waiting for almost 8 million Pfizer / BioNTech cans from a supply contract for more than 10 million. The government said most of it will be delivered before the end of September but cannot set fixed delivery dates.

Health Minister Enrique Paris said a strict weekly vaccination calendar, broken down by age group, was in place to ensure Chile has not used up its supplies before more have arrived.

“I think we have to be calm about it,” Paris told reporters at a briefing on Monday. “We have a lot of agreements with a lot of different companies and the vaccines are still coming.”

Chile, which vaccinated up to 430,000 people a day in March, has reached more than 50% of the 15 million people scheduled to be vaccinated with a single vaccine by July, while 36% received both doses.

However, the country was hit by a second wave of coronavirus in March, with the end of the summer vacation in the southern hemisphere and contagious virus variants first circulating in the UK and Brazil.

Santiago and parts of the country are strictly closed. Around 7,000 confirmed new COVID-19 cases are reported every day.

(Graphic: Chile vaccines: second dose: https://graphics.reuters.com/HEALTH-CORONAVIRUS/CHILE/gjnpwdlydvw/chart.png)

“Could be a lot worse”

Unlike countries that are widening the gap between first and second doses to provide some protection to more people, Chile now has priority over the first dose, according to Paris. The country is aiming to deliver 760,000 second shots this week as data shows that a single dose of the Sinovac shot offers little protection.

Chile released its own analysis last week of the limited effectiveness of Sinovac’s CoronaVac vaccine on its population. The shot was only 16% effective in preventing infection and 36% in keeping people out of the hospital after a dose.

“If we don’t give the second dose, the situation could be much worse,” said Paris.

In comparison, the risk of infection decreased by 80% two weeks or more after the first Pfizer / BioNTech shot, according to the U.S. Centers for Disease Control and Prevention.

In addition to the first AstraZeneca doses expected to arrive via COVAX, the Minister of Health has signed a contract to purchase 1.8 million doses of a single vaccine from CanSino Biologics, according to Chile.

Rodrigo Yanez, the Chilean vice minister of trade in charge of purchasing COVID-19 vaccines, told Reuters on Friday that the country’s rapid vaccination campaign has made it an “attractive springboard” for vaccine manufacturers to test their wares. He said he was confident he could keep the supply taps open.

Yanez said his team had pushed Sinovac to ship an additional 4 million cans and that the first of 4 million cans purchased directly from AstraZeneca should arrive in May.

He said Chile had also spoken to Sinopharm and India about purchasing a Covaxin vaccine and was in “advanced” talks with the Russian Direct Investment Fund to purchase 5 million doses of the Sputnik V vaccine for delivery this year or next .

“We planned to put various vaccines on and off,” said Yanez, adding that Pfizer will be widely used in the program. “We are confident and confident that we can achieve herd immunity by the middle of the year.”


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